This report details a National Institute of Justice, grant funded project designed to investigate the potential use of novel methods and testing that facilitate the rapid identification and quantitation of various drugs as an alternative to conventional testing.
It was demonstrated that a simple acetone extraction from blood was suitable for liquid chromatography/mass spectrometer/mass spectrometer (LC/MS/MS) analysis of a wide range of drugs encountered in forensic samples. During the project, methods were developed that facilitated rapid identification and quantitation of over 100 different drugs. There were some drugs (e.g. morphine, hydromorphone, and THCA) that did not produce adequate sensitivity or were not detected because of early elution from the column. It was also determined that some drugs had degraded during storage of blood samples. This type of information could prove important in cases where a significant time interval has elapsed between death or sample collection and the subsequent analysis.
Downloads
Similar Publications
- Discussion of the FTCOE’s Guidance Document on Considerations for Photographic Documentation in Sexual Assault Cases
- Evidence-Based Evaluation Of The Analytical Schemes In ASTM E2329-17 Standard Practice For Identification Of Seized Drugs For Methamphetamine Samples
- White Paper – Information Sharing Between Medicolegal Death Investigators And Toxicology Testing Services